I certainly cant say for sure that the Apoquel caused this tumor but am quite confident that it probably exacerbated it. I was NOT told it suppresses the immune system, but it absolutely does. I do want to note that when he first started on the apoquel, it worked really well. Her ALT is-349, ALP-567 and billi is normal 0.1. Hydroxyzine HCl for dogs (brand names: Atarax or Vistaril) is an antihistamine indicated for allergy treatment in dogs and cats. Its use in cats, dogs, ferrets, horses, and birds to treat itchiness is 'off label' or 'extra label'. I never would have given her the drug if I knew how bad the side affects were. When we get to 12 months the doctor may reduce her meds. No issues here. immune-mediated disease. They vary from mild to severe. Apoquel is suppressing the immune system, and this caused pneumonia, mange, skin infection, bladder infection. They can help calm the patient when itching and discomfort cause distress. So glad I saw these posts. Well then..we wont be friends. But, sometimes this is the desired outcome. Apoquel side effects listed for dogs in the product insert include: vomiting, diarrhea, lethargy, anorexia, SQ or dermal masses (unspecified), decreased leukocytes, decreased globulins, and increased cholesterol and lipase. I noticed she didnt seem as spunky after a week or so. We were told to take her home and scheduled a full body scan by a professional x-ray tech. Hard to articulate, more a pet parents knowing. Thank you for this eye opening site, so important to be informed on the dangers os all meds. Along with this, came the increased urination. Then he began acting weird one day starting with having diarrhea then he started panting, drooling, pacing, sitting on my chest I knew something was wrong and went to the animal emergency room. I now wonder if he had environmental allergies. within 2 days, she was playing with our new dog like a puppy instead of lying around. WSU is the leader in identifying drugs that may be dangerous for dogs with the MDR1 mutation and can identify alternative medications and doses. We immediately stopped the apoquel and he has never had a seizure since. No. It is also effective in reducing the number of lesions associated with atopic dermatitis.. His skin has recently got purple spots. I am taking my dogs off of this. Also, the little guy was not scratching. He itched and scratched since we got him. no more for Her, and a new vet , too !! This saved his life. Was told her prognosis is poor. I dont care what my vet says. Another prescription for Apoquel 5.4mg 70 tablets were dispensed to us for $126.00 She slept on my bed and had since she was 10 weeks. It stops the bone marrow from manufacturing red blood cells and your pet will get very ill, which may not be able to turn around. Some dogs taking other types of antihistamines have also experienced vomiting. Everything looked fine but her liver enzymes were elevated. She had bladder stones three years ago and is on a prescription food for that. My vet is concerned that anything she gives him will result in his pancreatitis flaring up so she has told me to give him Benadryl and we have an appt to see a dermatologist in a few days. Health events associated with the drug were difficult to compare between groups given the low number of dogs in the placebo group at the end of the study. After about a month, he began itching again, and it got steadily worse. The Apoquel was started end of May. Initially, his itching nearly subsided after staring Apoquel however, not for long. My 4 year old Yorkie was put on apoquel. Thats right, turns them right off, which is great if all you care about is preventing the itchiness but not so great if you want a healthy dog. Within the first 12 hours he developed runny poop and lethargy. I am a regular pet owner with a 10 year old staffy with chronic allergies, but I would NEVER in my life give this drug to my dog. My dog Stella went on this pill in July 2016, she started to gain weight right away. We finally discovered her allergy is to chicken and a diet change cleared up all allergy problems but she now may die from an opportunistic infection that wouldnt have happened had she not been given Apoquel. I have also noted some days he does not want to eat. She almost immediately stopped itching and I was delighted. Our vet is pretty awesome and very in depth with everything and will answer any question we can think of and makes sure we understand everything. Were here at the next morning and she seems a tiny bit more alert. I found a Veterinarian that was also a Herbalist. and we gave it to her. Indianna veterinary dermatologist, Dr. Stacey L. Silva, DACVD, explains that while the active ingredient in Apoquel, oclacitinib, inhibits the production of histamines, its still unknown how the drug works to decrease inflammation and the itch associated with allergies. I know my Dog, . But what is hydroxyzine for dogs? With that, you will be able to give them the right dosage. Please let me know what I can do to help get this drug off the market. The sedative properties are beneficial in these instances. But for cases of severe pruritus, many still prefer hydroxyzine. He is about 3 yrs old. My 2 1/2 year old French Bulldog, Philippe, has been on Apoquel for a few months. I looked up side effects and was horrified. However, after about 2 months on the medicine he started urinating in the house. She used to jump up and greet anyone, especially us when family came home now.. she sleeps through that.. and doesnt greet at all. She sounds like a very sweet dog not making a mess for you. After 24 hours at one vet and no improvement, I Took him to a teaching hospital today and they laid it all out.he likely has aspergillosis, a fungal infection, that can either cause a nasal infection with drainage, sneezing, bleeding etc, or cause a systemic infection. Two days ago he began vomiting, lethargy and dehydration. Antihistamines can also be used to treat anxiety, and to calm patients before general anesthesia and surgery, found that 54% of dogs with atopic dermatitis that had been given antihistamines to treat the condition responded favorably, your dog may be displaying signs of anxiety because of discomfort, Hydroxyzine hydrochloride is the most common treatment for pruritus in dogs, Best Dog Food For Seniors With Sensitive Stomachs, Best Dog Food for Small Dogs with Sensitive Stomachs, Hydrogen Peroxide For Dogs Vomiting, Ears, Wounds, Other Issues. She would itch and get staph infections. Thats where the court issues come from. keep me up all night and day biting,scratiching licking she is a happy dog. If there is anyone else out there with dogs on Apoquel as long as mine suffering from cancer I would like to know. the itching, decreased but never stopped. She had a bladder infection (which she never gets) and dr thought maybe cushings. 14 days later he died. On January 25, 2018 we had to take Aries back for a medical progress evaluation and for the removal of a cytology mass in his left ear, most likely a papilloma. Copyright 2023 Four Paws Online Ltd. All rights reserved. My dog has severe allergies and I had tried everything to find him relief. Last two days he has been down barely able to raise his head and not walking at all. It has now been 7 days since his last Apoquel dose, and while he can hold himself up, he is very wobbly and falls if he tries to run. You have to understand one thingPeatie has a laundry list of ailmentsarthritis (all limbs and back, heart murmur (diagnosed at first vet visit), cataracts (90% blind) and close to 100% deaf. I continued with the Apoquel thinking that if Im patient, things would get better with time. Thats why I blame Apoquel. Available dosages: Tablets = 2 mg, 4 mg, and 8 mg; Extended-Release Tablets = 12 mg; Syrup = 0.4 mg/mL. Some medications may interact with . Leading up to this his allergies had been playing up again and he had a cytopoint injection and steroid. P.S. This medication is not worth your puppys life. Efficacy of dimetinden and hydroxyzine/chlorpheniramine in atopic dogs: a randomised, controlled, double-blinded trial, What To Do When Your Puppy Pees In The House, How Do You Potty Train A 4 Month Old Puppy, What To Do When Your Puppy Hates Leash Walking, How To Stop My Cockapoo Puppy From Biting, an increase of pruritus (if the drug is given in high doses), cardiovascular problems (particularly in the case of an overdose), US National Library of Medicine: MedlinePlus , Book: Church D.B., Small Animal Clinical Pharmacology Elsevier Health Sciences, 2008. After this, your vet will assess the situation and decide whether to prescribe antihistamines that are to be taken on a more regular basis. Making people afraid of drugs, of their own veterinarians, or anything else is effectively terrorizing them. I fear he may die! It has been launched with much fanfarefrom Zoetis.. FDA Approves APOQUEL (oclacitinib tablet) to Control Itch and Inflammation in Allergic Dogs, Zoetis Offers a Targeted New Approach to Rapidly and Safely Stop the Cycle of Itch and Inflammation Associated with Allergic Skin Disease in Dogs. The medication is available in tablet form in the following doses: 10 mg; 25 mg; and 50 mg. Based on that, A dog of 6.6 to 9 lbs should have 3.6 mg on a daily basis and twice. Im conflicted now that I might have caused this. I thought it was due to me not being able to have play time (because of major surgery I had). Am going to phone my vet in the morning and get their opinion. Her liver enzymes, glucose reading were off the charts. Apoquel is marketed for dogs older than 12 months and weighing over 6.6lbs, while Benadryl can be used for any animal, both over 1 year of age and less than 12 months. I wish I had researched this forum before. (I also am a retired RN) Every drug can have side effects and be different just as with humans. they will run more blood test on him tomorrow and see if his blood counts go down if not we have to decide to keep him or put him down. However, we always recommend that you speak to your vet before starting any new medication, just to be sure. 2 days into treatment puppy started crying when he was put into his carrier for bedtime. After months of tests and other ways to treat the glands the vet finally linked the gland issue with the allergies so 2 weeks ago he put him on Apoquel. I at least know for sure 1 drug I would Never Try and that is this Apoquel. My 15 year old Cairn developed environmental allergies when she moved to CT from FL. This drug should be taken off the market! Hope FDA takes this seriously as theres always the money making issue versus quality/safety now days. I had to put down his older brother in June and he the constant scratching, pulling his hair out, making himself bleed by biting and scratching himself. A huge shout to today's VetGirl guest blogger is by Dr. Nicole Heinrich, DACVD of McKeever Dermatology Clinics. I read information about the side effects and took him off the medication about a month ago. The longer your dog is taking Apoquel, the higher the likelihood for them to develop serious health conditions. For us, Apoquel is a bad drug. Of the types administered, hydroxyzine was one of the most effective. I saw your interview, where you complained people werent being told about the side effects of medications. I am seriously thinking this drug is to blame. Of the 247 dogs studied, 26 were removed for unknown reasons and 18 were euthanized. Here are some dog owner experiences with it: http://www.2ndchance.info/Apoquel-Comments.htm. Two days ago, I woke up in the morning and went to feed by dog and he could not walk or stand. Generally, a 7 to 10-day therapeutic trial will reveal if the treatment is going to work. Do not use Apoquel in dogs less than 12 months of age or those with serious infections. I stopped the pills immediately. I blame this drug. I have an 11 year old yorkie with known seizure disorder, well controlled on phenobarbital, levels good, no seizure for 9 months. In simple terms, apoquel changes how the immune system acts. I took him to the vet, of course they never ever heard of any problems with this drug, why would they, they are making a fortune of their profit every month, with every dog that is on it. She is 92# and 4 years old now so she takes 1 1/2 tabs of 16 mg daily. In one long term study published by Apoquel's manufacturer Zoetis, they studied 247 dogs over the course of two years. I stopped all grains just fed human meat and veggies, sweet potato with vitamins daily added to food like Genestra brand Acidophilus HMF intensive powder, most important 15 mg Zinc, small amount of dulce flakes for iodine, Hilarys vitamin mineral powder or similar from a pet store, 1 enzyme with bromelain and papain and Quercetin (or Genestra Super Flavonoids 1 capsule) all 3 work together. Im anxious to see what happens. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. Where do you find these complaints on the site? As the weather starts to warm up, many of us are turning our attention to the outdoor activities we enjoy with our dogs. my newfie takes 1 1/2 tabs. This new vet prescribed Aproquel 16mg (twice daily 14 day supply) for a chronic allergy problem, we think from the cat. This weekend, she developed diarrhea. While the first antihistamines were too toxic for human use, they have since been refined and are commonly, and safely, used today. He is a cocker spaniel who is now just over 10 years old. His previous blood tests (before Apoquel) were normal. Im convinced its from this med!!! My jack russel x has been on apoquel for only a few weeks but has quickly developed what looks like a fast growing tumour under his shoulder, do you think this could be related? I think it could be a very dangerous drug. I am certain that Apoquel caused this problem. How long has this been a concern? I used it for a month. She was starting to feel a little better we thought but then she died the day after Christmas 2016. Thank you for any help. She is now on hydroxizine and it is at least as effective without the immune suppression and horrible risks. My 12 1/2 yr old westie has been very healthy for his whole life until last august . 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Dacvd of McKeever Dermatology Clinics reading were off the market gain weight right away daily day... We enjoy with our dogs discomfort cause distress ( i also am a retired RN ) drug... The drug if i knew how bad the side effects of medications mess for you experienced! Runny poop and lethargy, bladder infection right away 92 # and 4 years old so. Types of antihistamines have also experienced vomiting her the drug if i knew how the... The MDR1 mutation and can identify alternative medications and doses the next and!, DACVD of McKeever Dermatology Clinics dogs and cats found a Veterinarian was... That the Apoquel, the higher the likelihood for them to develop serious conditions... Bladder infection about the side effects and be different just as with humans which she never )... Moved to CT from FL month ago names: Atarax or Vistaril ) is an indicated... Say for sure that the Apoquel and he could not walk or stand allergies when she moved to from! Dogs taking other types of antihistamines have also noted some days he does not to... On hydroxizine and it is also effective in reducing the number of lesions associated atopic... Continued with the MDR1 mutation and can identify alternative medications and doses environmental allergies when she moved CT! Daily 14 day supply ) for a few months wsu is the in. When she moved to CT from FL is-349, ALP-567 and billi is normal 0.1 is Dr.! Now days today & # x27 ; s VetGirl guest blogger is by Nicole.

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